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DeCS
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Descriptor English:
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Werner Syndrome Helicase
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Descriptor Spanish:
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helicasa del síndrome de Werner
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Descriptor Portuguese:
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Helicase da Síndrome de Werner
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Synonyms English:
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Helicase, Werner Syndrome
RECQ3 Protein
RECQL2 Protein
Werner Syndrome ATP Dependent Helicase
Werner Syndrome ATP-Dependent Helicase
Werner Syndrome RecQ Like Helicase
Werner Syndrome RecQ-Like Helicase
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Tree Number:
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D08.811.277.040.025.159.249.500
D08.811.277.352.335.375.875
D08.811.277.352.365.290.500
D08.811.399.340.249.500
D12.776.157.687.750
D12.776.660.720.750
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Definition English:
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A DNA-dependent helicase and 3'-5' exonuclease. It has 3'->5' exonuclease activity towards double-stranded DNA with a 5'-overhang and binds preferentially to DNA substrates containing alternate secondary structures, such as replication forks and HOLLIDAY JUNCTIONS. Mutations in the WRN gene are associated with WERNER SYNDROME. |
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History Note English:
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2017
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Allowable Qualifiers English:
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Record Number:
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56469
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Unique Identifier:
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D000071657
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Occurrence in VHL:
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Similar:
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DeCS
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